178119-93-2 Usage
Description
Fmoc-D-4-Hydroxyphenylglycine is a chemical compound that plays a crucial role in the synthesis of peptide compounds. It is a 4-hydroxyphenylglycine amino acid derivative featuring a fluorenylmethyloxycarbonyl (Fmoc) protecting group attached to the amino group. Fmoc-D-4-Hydroxyphenylglycine is instrumental in solid-phase peptide synthesis, providing a stable and soluble intermediate for the formation of peptide chains. Its structural and functional properties make it an essential component in the development of peptide-based drugs and research materials.
Uses
Used in Pharmaceutical Industry:
Fmoc-D-4-Hydroxyphenylglycine is used as a building block for the synthesis of peptide-based drugs. Its presence in the synthesis process allows for the creation of a wide range of bioactive peptides with specific therapeutic properties. Fmoc-D-4-Hydroxyphenylglycine's stability and solubility contribute to the efficient production of these drugs, enhancing their effectiveness in treating various medical conditions.
Used in Research and Development:
Fmoc-D-4-Hydroxyphenylglycine is utilized as a key component in the development of novel peptide-based research materials. Its unique structural properties enable the exploration of new peptide sequences and their potential applications in various scientific fields. Fmoc-D-4-Hydroxyphenylglycine's versatility in solid-phase peptide synthesis facilitates the design and synthesis of innovative peptides for research purposes.
Used in Peptide Synthesis:
Fmoc-D-4-Hydroxyphenylglycine is used as a protected amino acid in solid-phase peptide synthesis. The Fmoc protecting group ensures that the amino group remains unreactive during the synthesis process, allowing for the stepwise addition of other amino acids to form the desired peptide chain. This method streamlines the synthesis process and improves the overall yield and purity of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 178119-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,1,1 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 178119-93:
(8*1)+(7*7)+(6*8)+(5*1)+(4*1)+(3*9)+(2*9)+(1*3)=162
162 % 10 = 2
So 178119-93-2 is a valid CAS Registry Number.
178119-93-2Relevant articles and documents
Preparation method of amoxicillin
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Paragraph 0027-0029, (2019/12/25)
The invention provides a preparation method of amoxicillin. The amoxicillin is obtained by synthesis of amino protected raw materials, the reaction route is short, product purity is high, operation iseasy, and wide industrial application prospects are achieved.
A facile Fmoc solid phase synthesis strategy to access epimerization-prone biosynthetic intermediates of glycopeptide antibiotics
Brieke, Clara,Cryle, Max J.
supporting information, p. 2454 - 2457 (2014/05/20)
A rapid protocol based on Fmoc-chemistry for the solid phase peptide synthesis of vancomycin- and teicoplanin-type peptides is described. Epimerization of highly racemization-prone arlyglycine derivatives is suppressed through optimized Fmoc-deprotection
