17820-07-4 Usage
General Description
Nordentatin is a natural chemical compound found in the roots of the plant Gelsemium elegans, also known as the heartbreak grass. It is a type of alkaloid, a class of naturally occurring organic compounds that contain basic nitrogen atoms. Nordentatin has been studied for its potential use in medicine due to its ability to bind to and inhibit the activity of certain receptors in the nervous system, which may have applications in the treatment of pain and anxiety. Additionally, it has also been found to have potential anticancer and anti-inflammatory properties, making it a subject of interest for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 17820-07-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,8,2 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17820-07:
(7*1)+(6*7)+(5*8)+(4*2)+(3*0)+(2*0)+(1*7)=104
104 % 10 = 4
So 17820-07-4 is a valid CAS Registry Number.
InChI:InChI=1/C19H20O4/c1-6-18(2,3)14-16-11(7-8-13(20)22-16)15(21)12-9-10-19(4,5)23-17(12)14/h6-10,21H,1H2,2-5H3
17820-07-4Relevant articles and documents
Synthesis and cytotoxicity of coumarin derivatives and nordentatin
Promsuwan, Pawantree,Yenjai, Chavi
, p. 3629 - 3632 (2013/05/09)
Nordentatin and 10 coumarin derivatives were synthesized and evaluated for cytotoxicity. Compounds 6, 7, 9 and 13 showed cytotoxicity against the NCI-H187 cell line with IC50 value ranging of 3-7 μg/mL. Among synthesized coumarins, compounds 4 and 13 demonstrated cytotoxicity against the KB cell line with IC50 values of 3.94 and 6.44 μg/mL, respectively. Fortunately, coumarins 4 and 7 may be one of the new lead compounds for the development of anticancer agents due to reason that they showed weak and inactive against normal cells.
