18529-17-4Relevant articles and documents
Facile one-pot multicomponent synthesis of highly functionalized tetrahydropyridines using thiamine hydrochloride as an organocatalyst
Singh, Sandeep,Gupta, Annah,Kapoor, Kamal K.
, p. 1056 - 1063 (2020)
Thiamine hydrochloride (VitB1) has been found to be an efficient catalyst for the multicomponent synthesis of highly functionalized tetrahydropyridines from the reaction of β-ketoester, aromatic aldehydes and anilines. VitB1 is easily available, cheap, and eco benign.
Ecofriendly and facile Nano ZnO catalyzed solvent-free enamination of 1,3-dicarbonyls
Indulkar, Utkarsha U.,Kale, Sandip R.,Gawande, Manoj B.,Jayaram, Radha V.
supporting information; experimental part, p. 3857 - 3860 (2012/08/27)
Nano zinc oxide (Nano-ZnO) was explored as a reusable catalyst for the enamination of 1,3-dicarbonyls using diverse amines. To make the process environmentally viable, the reaction was carried out under solvent-free conditions and found to give good yield of desired products. The catalyst was characterized by various analytical techniques such as UV-spectroscopy, XRD, and TEM. The catalyst was found to be reusable up to four catalytic cycles without any appreciable loss in activity.
A facile, chemoselective and eco-friendly solid phase synthesis of enaminones catalyzed by L-Proline
Bhupathi, Raja S.,Devi, B.Rama,Dubey
experimental part, p. 5521 - 5524 (2012/07/13)
A facile and chemoselective method for the synthesis of enaminones by the reaction of aromatic primary amines with various β-ketoesters in the presence of L-proline as activator under solid phase is described. The reactions are promoted by the catalyst in short time (5-6 min) under ambient conditions, without any side products.
