18830-59-6Relevant articles and documents
Synthesis and A1-adenosine receptors affinities of purino[7,8- c]quinazoline-8,10(9H,11H)-diones as rigid analogues of 8-arylxanthines
Ceccarelli,D'Alessandro,Magnante,Scuri,Zanarella
, p. 1301 - 1312 (2007/10/02)
Title compounds were prepared by a cyclocondensation reaction between 8- (2-aminophenyl)xanthines and trialkyl orthoesters. Some of them showed activities as A1-adenosine receptor antagonists with binding values in the micromolar range. Results