190381-50-1 Usage
General Description
Imidazo[1,2-a]pyrazine-3-carboxylic acid, 2,6-dimethyl- (9CI) is a chemical compound with the molecular formula C9H8N2O2. It is a heterocyclic compound containing an imidazole ring fused to a pyrazine ring, and a carboxylic acid group at the C-3 position. The compound also has two methyl groups at the C-2 and C-6 positions. Imidazo[1,2-a]pyrazine-3-carboxylic acid, 2,6-dimethyl- (9CI) has potential applications in pharmaceutical research and can be used as a building block in the synthesis of various pharmaceutical compounds. Additionally, it may have biological activities and effects, making it a subject of interest in medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 190381-50-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,3,8 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 190381-50:
(8*1)+(7*9)+(6*0)+(5*3)+(4*8)+(3*1)+(2*5)+(1*0)=131
131 % 10 = 1
So 190381-50-1 is a valid CAS Registry Number.
190381-50-1Relevant articles and documents
Research on heterocyclic compounds. XXXVII. Synthesis and antiinflammatory activity of methyl-substituted imidazo[1,2-a]pyrazine derivatives
Rimoli,Avallone,De Caprariis,Luraschi,Abignente,Filippelli,Berrino,Rossi
, p. 195 - 203 (2007/10/03)
A series of methyl-substituted imidazo[1,2-a]pyrazines 8 bearing a carboxylic acid group on the imidazole ring were synthesized. The structures of new compounds were confirmed by 1H- and 13C-NMR spectral data; the correct assignment of carbon resonances was made by means of HETCOR and COLOC experiments. Antiinflammatory, analgesic and ulcerogenic activities in vivo were evaluated and compared with those of antiinflammatory imidazopyrazines (2 and 3) and indomethacin. The inhibitory action on cyclooxygenase activity was evaluated in vitro. Compounds 8 were found to be less potent than indomethacin in these assays. SARs are discussed.
