19977-29-8Relevant articles and documents
Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents
Zagórska, Agnieszka,Bucki, Adam,Ko?aczkowski, Marcin,Siwek, Agata,G?uch-Lutwin, Monika,Starowicz, Gabriela,Kazek, Grzegorz,Partyka, Anna,Weso?owska, Anna,S?oczyńska, Karolina,P?kala, El?bieta,Paw?owski, Maciej
, p. 10 - 24 (2016/12/16)
A series of 2-fluoro and 3-trifluoromethylphenylpiperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione (4–21) were synthesized and evaluated for their serotonin (5-HT1A/5-HT7) receptor affinity and phosphodiesterase