29898-32-6 Usage
Description
1,3-Dichloro-4-iodobenzene is an organic compound with the chemical formula C6H3Cl2I. It is a clear, colorless to light yellow liquid and is known for its participation in various chemical reactions, such as the Ullmann coupling reaction.
Uses
1. Used in Chemical Synthesis:
1,3-Dichloro-4-iodobenzene is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows it to be a valuable building block in the creation of more complex molecules.
2. Used in the Preparation of Commercial Polychlorobiphenyls:
1,3-Dichloro-4-iodobenzene is used as a starting material in the preparation of 2,4,2′,4′-tetrachlorobiphenyl, which is a major component of commercial polychlorobiphenyls (PCBs). PCBs have been widely used in the past for various industrial applications, such as in transformers and capacitors, due to their heat resistance, chemical stability, and insulating properties.
3. Used in the Ullmann Coupling Reaction:
1,3-Dichloro-4-iodobenzene is utilized in the Ullmann coupling reaction, a chemical process that involves the formation of a carbon-carbon bond between two aryl or vinyl halides in the presence of a metal catalyst. This reaction is significant in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 29898-32-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,8,9 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 29898-32:
(7*2)+(6*9)+(5*8)+(4*9)+(3*8)+(2*3)+(1*2)=176
176 % 10 = 6
So 29898-32-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H3Cl2I/c7-4-1-2-6(9)5(8)3-4/h1-3H
29898-32-6Relevant articles and documents
Metathesis-active ligands enable a catalytic functional group metathesis between aroyl chlorides and aryl iodides
Lee, Yong Ho,Morandi, Bill
, p. 1016 - 1022 (2018/09/06)
Current methods for functional group interconversion have, for the most part, relied on relatively strong driving forces which often require highly reactive reagents to generate irreversibly a desired product in high yield and selectivity. These approaches generally prevent the use of the same catalytic strategy to perform the reverse reaction. Here we describe a catalytic functional group metathesis approach to interconvert, under CO-free conditions, two synthetically important classes of electrophiles that are often employed in the preparation of pharmaceuticals and agrochemicals—aroyl chlorides (ArCOCl) and aryl iodides (ArI). Our reaction design relies on the implementation of a key reversible ligand C–P bond cleavage event, which enables a non-innocent, metathesis-active phosphine ligand to mediate a rapid aryl group transfer between the two different electrophiles. Beyond enabling a practical and safer approach to the interconversion of ArCOCl and ArI, this type of ligand non-innocence provides a blueprint for the development of a broad range of functional group metathesis reactions employing synthetically relevant aryl electrophiles.
PROCESS FOR THE PREPARATION OF IODIDES
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Page/Page column 34, (2012/01/05)
This invention is directed to a process for the preparation of high yield alkyl or aryl iodide from its corresponding carboxylic acid using N-iodo amides.