7012-37-5

Basic information

• Product Name: 2,4,4'-TRICHLOROBIPHENYL
• Synonyms: 2,4,4’-trichloro-1’-biphenyl;4,2',4'-Trichloro-1,1'-biphenyl;1,1'-Biphenyl,2,4,4'-trichloro-;2,4,4’-trichloro-bipheny;2,4,4'-Trichloro-1,1'-biphenyl;4,2’,4’-trichlorobiphenyl;k28;PCB-28
• CAS NO: 7012-37-5
• Molecular Formula: C₁₂H₇Cl₃
• Molecular Weight: 257.54
• EINECS: 230-293-2
• Product Categories: Alphabetic;TP - TZ
• Mol File: 7012-37-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 206-207℃
• Boiling Point: 334.36°C (rough estimate)
• Flash Point: 100 °C
• Appearance: /
• Density: 1.3510 (rough estimate)
• Refractive Index: 1.6040 (rough estimate)
• Storage Temp.: 2-8°C
• Water Solubility: 116ug/L(25 oC)
• BRN: 1956846
• CAS DataBase Reference: 2,4,4'-TRICHLOROBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,4'-TRICHLOROBIPHENYL(7012-37-5)
• EPA Substance Registry System: 2,4,4'-TRICHLOROBIPHENYL(7012-37-5)

Safety Data

• Hazard Codes: N,Xn,F
• Statements: 33-50/53-11-67-65-38
• Safety Statements: 35-60-61-62-33-29-16
• RIDADR: 2315
• WGK Germany: 3
• RTECS: DV8840000
• HazardClass: 9
• PackingGroup: II
• Hazardous Substances Data: 7012-37-5(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 29898-32-6 2,4-dichloro-1-iodo-benzene 
• 1679-18-1 4-Chlorophenylboronic acid 
• 554-00-7 2,4-Dichloroaniline 
• 52388-33-7 1-(2,4-Dichlorphenyl)-3,3-dimethyltriazen 
• 89566-59-6 di-(p-chlorophenyl)borinic acid 
• 21872-70-8 2,4-dichlorobenzenediazonium tetrafluoroborate 
• 20082-66-0 trimethyl(2,6-dichlorophenyl)silicium 
• 876070-70-1 (2,6-dichloro-3-iodophenyl)trimethylsilane 
• 1193-72-2 1-bromo-2,4-dichlorobenzene 
• 7012-31-9 4,4',6-Trichlor-2'-carboxy-biphenyl 

Downstream Products

• 34883-43-7 2,4'-dichlorobiphenyl 
• 2050-68-2 4,4'-dichlorobiphenyl 
• 33284-50-3 PCB 7 
• 7061-82-7 4,4'-Dichlor-2-biphenylcarbonsaeure 

Relevant articles and documents

Highly efficient palladium-catalyzed cross-coupling of diarylborinic acids with arenediazoniums for practical diaryl synthesis

A highly efficient cross-coupling of cost-effective diarylborinic acids with both isolatable and latent arenediazoniums, i.e. tetrafluoroborates and aryltriazenes, respectively, has been developed with a practical palladium catalyst system under base-free conditions in open flask at room temperature. A variety of electronically and sterically various biaryls, in particular, those bearing a coordinative ortho-substituent, could be obtained in good to excellent yields by using 0.3 mol% palladium acetate as catalyst. Features of the protocol including cost-effectiveness of diarylborinic acids, efficacy to heteroatom ortho-substituted substrates and high chemoselectivity to aryl chlorides have been clearly demonstrated in practical synthesis of fungicide Boscalid.

Regioselectivity of the methanolysis of polychlorinated biphenyls

Regioselectivity of the methanolysis of lower polychlorinated biphenyls with sodium methoxide in a mixture of methanol and DMSO at 100–130°С was studied. It was found that 2,4,4'-tricholobiphenyl is much more reactive than 2,4-dichlorobiphenyl. This results in different mechanisms of substitution. 2,4-Dichlorobiphenyl reacts with sodium methoxide by the elimination–addition mechanism to form four monosubstitution products in comparable quantities. 2,4,4'-Trichlorobiphenyl reacts with the methodixe ion by the classical SNAr mechanism, with preferential substitution of the 2-chlorine atom.

METHOD FOR SEPARATING AND CLEANING UP POLYHALOGENATED BIPHENYLS

The method for separating and cleaning up polyhalogenated biphenyls (PHBs) is characterized by comprising the following three steps: (1) the step of bringing a sample containing PHBs into contact with a fibrous activated carbon; (2) the step of washing the fibrous activated carbon with hexanes; and (3) the step of eluting PHBs from the fibrous activated carbon.