69875-54-3

• 

• Basic information

  1. Product Name: 3-Cyano-2,4-dichloroquinoline
  2. Synonyms: 3-Cyano-2,4-dichloroquinoline
  3. CAS NO:69875-54-3
  4. Molecular Formula: C₁₀H₄Cl₂N₂
  5. Molecular Weight: 223.05816
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 69875-54-3.mol
  9. Article Data: 10

• Chemical Properties

  1. Melting Point: 168-169 °C(Solv: ethanol (64-17-5))
  2. Boiling Point: 382.0±37.0 °C(Predicted)
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: 1.49
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. PKA: -4.42±0.50(Predicted)
  10. CAS DataBase Reference: 3-Cyano-2,4-dichloroquinoline(CAS DataBase Reference)
  11. NIST Chemistry Reference: 3-Cyano-2,4-dichloroquinoline(69875-54-3)
  12. EPA Substance Registry System: 3-Cyano-2,4-dichloroquinoline(69875-54-3)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 69875-54-3(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

69875-54-3 Suppliers

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• 3-Cyano-2,4-dichloroquinoline/High quality/Best price

  Cas No: 69875-54-3

• USD $ 1.0-1.0 / Gram

• 1 Gram

• 1-100 Metric Ton/Month

• Shanghai Massive Chemical Technology Co., Ltd.
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• 3-Cyano-2,4-dichloroquinoline

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• BOC Sciences
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• 3-Quinolinecarbonitrile, 2,4-dichloro- 69875-54-3

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• Hunan Russell Chemicals Technology Co.,Ltd
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• 3-Quinolinecarbonitrile, 2,4-dichloro- 69875-54-3

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• Shenzhen Foris Technology Co. LTD
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• 3-Cyano-2,4-dichloroquinoline

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• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• 3-Cyano-2,4-dichloroquinoline

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• 10 Milligram

• Amadis Chemical Co., Ltd.
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• 2,4-Dichloroquinoline-3-carbonitrile

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• ENAO Chemical Co, Limited
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• 3-Cyano-2,4-dichloroquinoline

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• Debye Scientific
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• 2,4-Dichloroquinoline-3-carbonitrile

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69875-54-3 Usage

General Description

3-Cyano-2,4-dichloroquinoline is a chemical compound with the molecular formula C10H5Cl2N. It is a heterocyclic compound and a derivative of quinoline. 3-Cyano-2,4-dichloroquinoline is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has been shown to have antifungal and antimicrobial properties, making it potentially useful in the development of new drugs. Additionally, 3-Cyano-2,4-dichloroquinoline has also been demonstrated to exhibit insecticidal and antiparasitic activities, further highlighting its potential importance in medicinal and agricultural applications.

Check Digit Verification of cas no

The CAS Registry Mumber 69875-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,8,7 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 69875-54:
(7*6)+(6*9)+(5*8)+(4*7)+(3*5)+(2*5)+(1*4)=193
193 % 10 = 3
So 69875-54-3 is a valid CAS Registry Number.

69875-54-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name	2,4-dichloroquinoline-3-carbonitrile

1.2 Other means of identification

Product number	-
Other names	2,4-dichloro-quinoline-3-carbonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69875-54-3 SDS

69875-54-3Upstream product

• 15000-43-8 2,4-dihydroxyquinoline-3-carbonitrile 
• 10026-13-8 phosphorus pentachloride 
• 10025-87-3 trichlorophosphate 
• 621-03-4 cyanoacetanilide 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 103-71-9 phenyl isocyanate 
• 1356125-45-5 3-cyano-2,4-dioxo-tetrahydroquinoline 
• 128366-07-4 4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid cyclohexylamide 
• 2651-12-9 ethyl 2-cyano-3-oxo-3-(phenylamino)-propanoate 
• 15000-43-8 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonitrile 
• 118-48-9 isatoic anhydride 

69875-54-3Downstream Products

• 34846-64-5 3-cyanoquinoline 
• 680210-85-9 4-chloro-2-oxo-1,2-dihvdroquinoline-3-carbonitrile 
• 1356125-46-6 N-[4-[[(3-cyano-2-(methylamino)quinolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide 
• 1356125-48-8 N-[4-[[(3-cyano-2-(propylamino)quinolin-4-yl)amino]methyl]phenyl]-4-fluorobenzamide 
• 16560-18-2 4-phenyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile 

69875-54-3Relevant articles and documents

Synthesis method of 2,4-dichloroquinoline compound

-

Paragraph 0078-0083, (2021/07/17)

The invention discloses a synthesis method of a 2,4-dichloroquinoline compound, belonging to the technical field of organic synthesis. The method comprises the following steps: at room temperature, mixing triphosgene and triphenylphosphine oxide, dissolving the mixture in an organic solvent, stirring for 10-30 minutes, adding an alpha-substituted acetyl arylamine compound, heating the reaction system to 90-130 DEG C, continuously stirring and reacting for 3-6 hours, and post-treating the obtained reaction liquid to obtain the 2,4-dichloroquinoline compound. The method for synthesizing the 2, 4-dichloroquinoline compound has the advantages of few steps, high yield and safer and more convenient operation; meanwhile, the triphenylphosphine oxide used in the reaction can be recycled, so that the emission of phosphorus-containing wastes is greatly reduced, and the method is suitable for industrial production.

PHENYL-CYANOQUINOLINONE PDE9 INHIBITORS

-

, (2017/02/24)

The present invention is directed to phenylcyanoquinolinone compounds which may be useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use

Design, synthesis, and biological evaluation of new diaminoquinazolines as β-catenin/Tcf4 pathway inhibitors

Mao, Yongjun,Lin, Nan,Tian, Wang,Han, Xiaofeng,Han, Xiaobing,Huang, Ziwei,An, Jing

, p. 1346 - 1359 (2012/04/04)

More than 50 new diaminoquinazoline derivatives have been synthesized and evaluated in a colon carcinoma cell growth inhibition assay using HCT116 and SW480 cells. Twenty compounds with good cell growth inhibitory activities (50 values 50 values of 1.5-2.5 μM for HCT116 cells with the luciferase reporter assay.

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