100002-37-7Relevant academic research and scientific papers
The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin v
Gazdik, Michelle,O'Neill, Matthew T.,Lopaticki, Sash,Lowes, Kym N.,Smith, Brian J.,Cowman, Alan F.,Boddey, Justin A.,Sleebs, Brad E.
supporting information, p. 437 - 443 (2015/03/18)
N-Methylation of the N-Cα peptide bond is a known strategy to overcome the liabilities inherently associated with peptide-like molecules. Here, we apply this strategy to transition state mimetics that are potent inhibitors of the malarial protease, plasme
New renin-inhibitory peptides and their use
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, (2008/06/13)
Compounds of formulaR 1 CO--NH--CH(R 2)--CONH--CH(R 3)--X[wherein:R 1 represents alkyl having an α-amino or protected α-amino substituent and an aryl, heterocyclic or heterocyclic-dithio substituent;R 2 represents a variety of aliphatic and cycloaliphatic
