1000045-69-1Relevant academic research and scientific papers
Efficient synthesis of 5-amino-6-dialkylamino-4-hydroxypentanamide derivatives for renin inhibitors
Nakamura, Yuji,Ogawa, Yasuyuki,Suzuki, Chie,Fujimoto, Teppei,Miyazaki, Shojiro,Tamaki, Kazuhiko,Nishi, Takahide,Suemune, Hiroshi
, p. 1587 - 1602 (2011)
We report an efficient synthetic method for 5-amino-6-dialkylamino-4- hydroxypentanamide derivatives using Shi Asymmetric Epoxidation and the ring opening of N-(2-nitrobenzenesulfonyl)aziridine with hindered secondary amine as key steps. The Japan Institute of Heterocyclic Chemistry.
