100008-35-3

Upstream product

• 75802-22-1 1-ethoxyisochromane 
• 93-55-0 1-phenyl-propan-1-one 
• 493-05-0 isochromane 

Downstream Products

• 83179-46-8 2-methyl-3-phenylnaphthalene 

Relevant academic research and scientific papers

Visible-light induced enhancement in the multi-catalytic activity of sulfated carbon dots for aerobic carbon-carbon bond formation

The development of carbonaceous materials as metal-free catalysts integrating different types of catalysis in a single system represents a significant advance in cascade/tandem organic synthesis. Zero-dimensional carbon dots with tuneable optical properties and easily modifiable surface functionalities can be harnessed as a carbocatalyst for merging photooxidation and acid-catalyzed reactions in one pot. Herein, we explore carbon dots decorated with hydrogen sulfate groups as a photocatalyst for the dehydrogenative cross-coupling of xanthenes with ketones, arenes and 1,3-dicarbonyl compounds that showed high efficiency and selectivity under visible-light irradiation. The sulphated carbon dots demonstrate dual catalytic properties, wherein they induced the rapid photooxidation of xanthenes in the presence of molecular oxygen to form a hydroperoxy intermediate followed by coupling of nucleophiles catalysed by the acidic surface functional groups. The methodology represents an operationally simple pathway for the generation of C-C coupling products in a short reaction time with wide substrate scopes under mild conditions. The catalyst is easily separable and can be reused over multiple cycles with good efficiency.

Catalytic amounts of CBr4 mediated dehydrogenative coupling of isochromans with aromatic ketones

In the presence of catalytic amounts of CBr4 (a metal-free mediator), an unexpected oxidative dehydrogenative coupling of isochromans with ketones occurred to construct new Csp3-Csp3 bonds. The reactions were performed und

Copper(II) catalyzed cross-dehydrogenative coupling of cyclic benzylic ethers with simple carbonyl compounds by Na2S2O 8

Copper(II) catalyzed cross-dehydrogenative coupling of cyclic benzylic ethers with a variety of simple carbonyl compounds mediated by Na 2S2O8 is developed. The scope of carbonyl components is broad, including simple aldeh

Manganese dioxide-methanesulfonic acid promoted direct dehydrogenative alkylation of sp3 C-H bonds adjacent to a heteroatom

A manganese dioxide (MnO2)-methanesulfonic acid (CH 3SO3H) oxidation system has been developed to efficiently promote direct coupling of benzylic ethers and carbamates with simple ketones via oxidative C-H bond activation.

Oxidative alkylation of cyclic benzyl ethers with malonates and ketones using oxygen as the terminal oxidant

A simple oxidative alkylation of cyclic benzyl ethers with malonates and ketones was developed using a mixture of Cu(OTf)2, InCl3, and NHPI as catalyst under an atmospheric pressure of oxygen. Georg Thieme Verlag Stuttgart.

DDQ-mediated direct cross-dehydrogenative-coupling (CDC) between benzyl ethers and simple ketones

A direct Cross-Dehydrogenative-Coupling (CDC) between benzyl ethers and simple ketones was developed without using any metal catalyst. By using DDQ, various benzyl ethers and simples ketones were coupled together directly to form β-alkoxyl ketones efficie

TRANSFORMATION OF (ISOCHROMAN-1-YL)METHYLENEKETONES TO NAPHTHALENE DERIVATIVES

Treatment of (isochroman-1-yl)methylketones (2c-h) with potassium tert-butoxide gave different naphthalene derivatives (5-14) via novel ring transformation, depending on the presence or absence and the nature of the substituents adjacent to the carbonyl group in 2.