1000304-34-6 Usage
Description
(1R,2R,5S,6R,7R)-6,8,8-TRIMETHYL-3-AZATRICYCLO[5.1.1.02,5]NONAN-4-ONE is a complex tricyclic chemical compound with a unique structure that contains a nitrogen atom and four chiral centers. The trimethyl substitution on the molecule contributes to its steric hindrance and influences its physical and chemical properties. (1R,2R,5S,6R,7R)-6,8,8-TRIMETHYL-3-AZATRICYCLO[5.1.1.02,5]NONAN-4-ONE may have potential biological activity and applications in drug discovery and medicinal chemistry.
Uses
Used in Drug Discovery:
(1R,2R,5S,6R,7R)-6,8,8-TRIMETHYL-3-AZATRICYCLO[5.1.1.02,5]NONAN-4-ONE is used as a potential candidate in drug discovery due to its interesting structure and possible biological activity.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (1R,2R,5S,6R,7R)-6,8,8-TRIMETHYL-3-AZATRICYCLO[5.1.1.02,5]NONAN-4-ONE is utilized for its potential to contribute to the development of new pharmaceutical compounds, given its unique structural features and the presence of a nitrogen atom.
Check Digit Verification of cas no
The CAS Registry Mumber 1000304-34-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,0 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1000304-34:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*0)+(3*4)+(2*3)+(1*4)=46
46 % 10 = 6
So 1000304-34-6 is a valid CAS Registry Number.
1000304-34-6Relevant articles and documents
Regio- and stereoselective synthesis of the enantiomers of monoterpene-based β-amino acid derivatives
Szakonyi, Zsolt,Martinek, Tamas A.,Sillanpaeae, Reijo,Fueloep, Ferenc
, p. 2442 - 2447 (2008/03/13)
The regio- and stereospecific addition of chlorosulfonyl isocyanate to cis-δ-pinene enantiomers has furnished monoterpene-fused β-lactams. The observed regioselectivity can be explained by ab initio DFT modeling of transition state structures. In contrast with the less reactive α-pinane-fused β-lactam 4, the resulting β-lactams 5 and 13 containing an amino group connected to a secondary carbon possess similar reactivity to the cycloalkane-fused analogues and can be easily converted to the β-amino acid and its protected derivatives. The base-catalyzed isomerization of the cis-amino ester afforded the corresponding trans-amino ester in moderate yield.
