1000305-04-3

Basic information

• Product Name: 1-{[(1S,2S)-2-(4-bromophenyl)cyclopropyl]methyl}-(2S)-2-methylpyrrolidine
• Synonyms: 1-{[(1S,2S)-2-(4-bromophenyl)cyclopropyl]methyl}-(2S)-2-methylpyrrolidine
• CAS NO: 1000305-04-3
• Molecular Weight: 294.235
• Mol File: 1000305-04-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-{[(1S,2S)-2-(4-bromophenyl)cyclopropyl]methyl}-(2S)-2-methylpyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[(1S,2S)-2-(4-bromophenyl)cyclopropyl]methyl}-(2S)-2-methylpyrrolidine(1000305-04-3)
• EPA Substance Registry System: 1-{[(1S,2S)-2-(4-bromophenyl)cyclopropyl]methyl}-(2S)-2-methylpyrrolidine(1000305-04-3)

Safety Data

• Hazardous Substances Data: 1000305-04-3(Hazardous Substances Data)

Upstream product

• 501922-16-3 (1S,2S)-[2-(4-bromophenyl)cyclopropyl]methanol 
• 105515-33-1 (2E)-3-(4-bromophenyl)prop-2-en-1-ol 
• 24393-53-1 ethyl (E)-3-(4-bromophenyl)-2-propenoate 
• 1366440-28-9 C₁₅H₁₈BrNO 
• 1366440-18-7 tert-butyl 2-(4-bromophenyl)cyclopropanecarboxylate 
• 77255-26-6 trans-2-(4-bromophenyl)cyclopropanecarboxylic acid 
• 1122-91-4 4-bromo-benzaldehyde 
• 350490-15-2 tert-butyl (E)-3-(4-bromophenyl)prop-2-enoate 
• 1000305-05-4 (1S,2S)-2-(4-bromophenyl)cyclopropanecarbaldehyde 

Downstream Products

• 1000305-12-3 4-{2-[(2S)-2-methyl-pyrrolidin-1-ylmethyl]-(1S,2S)-cyclopropyl}-phenylamine 

Relevant articles and documents

TREATMENT OF OSTEOARTHRITIS PAIN

This invention discloses a method of treatment of osteoarthritis pain by administration of a histamine H3 receptor antagonist, described herein, a salt thereof, or a composition comprising such compound or salt.

CYCLOPROPYL AMINE DERIVATIVES

Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compoun