100034-54-6

Upstream product

• 79154-57-7 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-N₆-benzoyladenosine 
• 4546-55-8 N-benzoyladenosine 

Downstream Products

• 205500-32-9 N-[9-((2R,3aR,9aR)-3-Hydroxy-5,5,7,7-tetraisopropyl-3-trimethylsilanylethynyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-9H-purin-6-yl]-benzamide 
• 424822-64-0 N⁶-benzoyl-9-{3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-C-[(trimethylsilyl)ethynyl]-β-D-arabinofuranosyl}adenine 
• 1378912-18-5 C₃₁H₄₇N₅O₇Si₂ 
• 1378912-20-9 C₃₂H₄₉N₅O₉SSi₂ 
• 1378912-22-1 C₃₁H₄₅N₅O₆Si₂ 
• 205500-36-3 9-[2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2'-C-ethynyl-β-D-arabinofuranosyl]-N⁶-(phenoxyacetyl)adenine 
• 205500-34-1 9-{2'-deoxy-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-C-[(trimethylsilyl)ethynyl]-β-D-arabinofuranosyl}-N⁶-(phenoxyacetyl)adenine 
• 205500-35-2 9-(2'-deoxy-2'-C-ethynyl-β-D-arabinofuranosyl)-N⁶-(phenoxyacetyl)adenine 

Relevant academic research and scientific papers

2'-Deoxy-2'(S)-ethinyl oligonucleotides: A modification which selectively stabilizes oligoadenylate pairing to DNA complements

Oligonucleotides consisting of 2'-deoxy-2'(S)-ethinyl-thymidine, -uridine, and -adenosine have been prepared. Whereas the modified pyrimidine oligonucleotides uniformly lead to weaker pairing affinity with DNA and RNA complements, the corresponding adenine oligonucleotides show enhanced thermal stability in duplexes with complementary DNA and decreased stability with RNA.