1000343-55-4 Usage
Description
3-IODO-5-NITRO-6-METHYL (1H)INDAZOLE is an organic compound characterized by its indazole structure, which features a fused indole and pyrazole ring system. The presence of an iodine atom at the 3-position, a nitro group at the 5-position, and a methyl group at the 6-position provides this molecule with unique chemical and biological properties. It is a key intermediate in the synthesis of various biologically active compounds.
Uses
Used in Pharmaceutical Industry:
3-IODO-5-NITRO-6-METHYL (1H)INDAZOLE is used as a reactant for the synthesis of alkenyl indazoles, which are selective Aurora kinase inhibitors. These inhibitors play a crucial role in the development of novel therapeutic agents for the treatment of various cancers, as Aurora kinases are overexpressed in several types of tumors and are involved in cell division and proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 1000343-55-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,4 and 3 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1000343-55:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*4)+(3*3)+(2*5)+(1*5)=64
64 % 10 = 4
So 1000343-55-4 is a valid CAS Registry Number.
1000343-55-4Relevant articles and documents
THERAPEUTIC AGENT FOR CEREBRAL INFARCTION
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, (2012/08/08)
The invention provides a therapeutic drug for ischemic stroke. The therapeutic drug has the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof, as an active ingredient.
