1000372-06-4Relevant academic research and scientific papers
Polymer-caged lipsomes: A pH-responsive delivery system with high stability
Lee, Sang-Min,Chen, Haimei,Dettmer, Christine M.,O'Halloran, Thomas V.,Nguyen, Sonbinh T.
, p. 15096 - 15097 (2007)
Polymer-incorporated liposomes were prepared from preformed liposomes and a cholesterol-functionalized poly(acrylic acid) additive via a simple drop-in procedure. These modified liposomes possess surface-active carboxylate groups that can be cross-linked with telechelic 2,2′-(ethylenedioxy)bis(ethylamine) linkers, resulting in polymer-caged liposomes (PCLs) that are highly stable and have tunable pH-sensitive responses. Copyright
COMPOSITIONS AND METHODS FOR POLYMER-CAGED LIPOSOMES
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, (2009/01/24)
The present invention provides liposomal compositions and methods of using such compositions in vitro and in vivo. In particular, the present invention provides stable, polymer-caged liposomes comprising a pH responsive delivery mechanism for delivery of
