227000-85-3

Basic information

• Product Name: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine
• Synonyms: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine
• CAS NO: 227000-85-3
• Molecular Formula: C₂₃H₃₂ClNO
• Molecular Weight: 373.95928
• Mol File: 227000-85-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 43-47°C
• Boiling Point: 461.3±55.0 °C(Predicted)
• Flash Point: >110℃
• Appearance: /
• Density: 1.043±0.06 g/cm3(Predicted)
• Storage Temp.: ?20°C
• PKA: 2.78±0.70(Predicted)
• CAS DataBase Reference: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine(227000-85-3)
• EPA Substance Registry System: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine(227000-85-3)

Safety Data

• Hazard Codes: O,C
• Statements: 8-34
• Safety Statements: 17-26-36/37/39-45
• RIDADR: UN 3085 8(5.1) / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 227000-85-3(Hazardous Substances Data)

Usage

Uses

Block Copolymer Synthesis Using a Commercially Available NMP Inititator

General Description

For a synthetic protocol using NMP initiators, contributed by Prof. Karen Wooley, please visit our technology spotlight.

Upstream product

• 85664-55-7 (Z)-2-methyl-N-(2-methylpropylidene)propan-2-amine N-oxide 
• 1592-20-7 4-Vinylbenzyl chloride 
• 61015-94-9 N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)-N-oxyl 

Downstream Products

• 895583-67-2 2,2,5-trimethyl-3-(1-(4-dioctylphosphorylmethyl)phenylethoxy)-4-phenyl-3-azahexane 
• 1079398-21-2 4-(1-(tert-butyl(2-methyl-1-phenylpropyl)aminooxy)ethyl)benzyl dodecyl carbonotrithioate 
• 1037074-91-1 C₄₄H₅₁NO₂S₂ 
• 1000372-06-4 N-tert-butyl-O-[1-(4-iodomethyl-phenyl)-ethyl]-N-(2-methyl-1-phenyl-propyl)-hydroxylamine 
• 1000372-07-5 N-tert-butyl-O-[1-(4-cholesterolmethyl-phenyl)-ethyl]-N-(2-methyl-1-phenyl-propyl)-hydroxylamine 
• 496816-90-1 2,2,5-trimethyl-3-(1'-p-((S)-(-)-2''-(t-butyl-oxy-carbonylamide)-3''-(p-oxyphenyl)-1'',1''-diphenylpropan-1''-ol)benzylethoxy)-4-phenyl-3-azahexane 
• 496816-88-7 2,2,5-trimethyl-3-(1'-p-(t-butyloxycarbonylamino)methylphenylethoxy)-4-phenyl-3-azahexane 
• 293328-23-1 2,2,5-trimethyl-3-(1'-p-aminomethylphenylethoxy)-4-phenyl-3-azahexane 
• 433266-98-9 2,2,5-trimethyl-3-(1'-(4''-hydroxymethyl)phenylethoxy)-4-phenyl-3-azahexane 
• 393110-71-9 O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine 
• 325468-29-9 2,2,5-trimethyl-3-(1'-(4''-acetoxymethyl)phenylethoxy)-4-phenyl-3-azahexane 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR POLYMER-CAGED LIPOSOMES

The present invention provides liposomal compositions and methods of using such compositions in vitro and in vivo. In particular, the present invention provides stable, polymer-caged liposomes comprising a pH responsive delivery mechanism for delivery of

Development of a universal alkoxyamine for "living" free radical polymerizations

Examination of novel alkoxyamines has demonstrated the pivotal role that the nitroxide plays in mediating the "living" or controlled polymerization of a wide range of vinyl monomers. Surveying a variety of different alkoxyamine structures led to α-hydrido derivatives based on a 2,2,5-trimethyl-4-phenyl-3-azahexane-3-oxy, 1, skeleton which were able to control the polymerization of styrene, acrylate, acrylamide, and acrylonitrile based monomers. For each monomer set, the molecular weight could be controlled from 1000 to 200 000 amu with polydispersities typically 1.05-1.15. Block and random copolymers based on combinations of the above monomers could also be prepared with similar control. In comparison with 2,2,6,6-tetramethylpiperidinoxy (TEMPO), these new systems represent a dramatic increase in the range of monomers that can be polymerized under controlled conditions and overcome many of the limitations associated with nitroxide-mediated "living" free radical procedures. Monomer selection and functional group compatibility now approach those of ATRP-based systems.