1000417-35-5Relevant academic research and scientific papers
Some new thiazolyl thiazolidinedione derivatives as aldose reductase inhibitors
Bozdag-Duendar, Oya,Evcimen, Net Das,Ceylan-Uenluesoy, Meltem,Ertan, Rahmiye,Sarikaya, Mutlu
, p. 39 - 47 (2007)
In diabetes, increased flux through the polyol pathway has been implicated in the development of diabetic complications such as cataract, retinopathy, neuropathy, and nephropathy. Aldose reductase (AR) appears to be the key factor in the reduction of gluc
