100059-65-2

Basic information

• Product Name: Benzoic acid, 4-(3-hydroxypropoxy)-3-methoxy-
• CAS NO: 100059-65-2
• Molecular Formula: C11H14O5
• Molecular Weight: 226.229
• Mol File: 100059-65-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(3-hydroxypropoxy)-3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(3-hydroxypropoxy)-3-methoxy-(100059-65-2)
• EPA Substance Registry System: Benzoic acid, 4-(3-hydroxypropoxy)-3-methoxy-(100059-65-2)

Safety Data

• Hazardous Substances Data: 100059-65-2(Hazardous Substances Data)

Upstream product

• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 627-30-5 1-chloro-3-hydroxypropane 
• 627-18-9 1-bromo-3-propanol 

Downstream Products

• 1337545-39-7 4-amino-5-(2-(4-(3-hydroxypropoxy)-3-methoxybenzamido)-2-methylpropoxy)-2-methylquinoline-3-carboxylic acid 
• 1337545-41-1 ethyl 4-amino-5-(2-(4-(3-hydroxypropoxy)-3-methoxybenzamido)-2-methylpropoxy)-2-methylquinoline-3-carboxylate 
• 1569080-16-5 C₂₃H₁₇FN₂O₄S 
• 1569084-58-7 C₂₆H₂₅FN₂O₅S 
• 226559-34-8 N-<5-methoxy-4-(2'-methoxycarbonylethoxy)-2-nitrobenzoyl>pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 226559-36-0 N-<2-amino-5-methoxy-4-(2'-methoxycarbonylethoxy)benzoyl>pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 219562-59-1 (2S)-2-hydroxymethyl-N-[4'-[[2''-(methoxycarbonyl)ethyl]oxy]-5'-methoxy-2'-[[[(trichloroethyl)oxy]carbonyl]amino]benzoyl]pyrrolidine 
• 219562-52-4 (2S)-N-[4'-[[2''-(methoxycarbonyl)ethyl]oxy]-5'-methoxy-2'-nitrobenzoyl]-2-(hydroxymethyl)pyrrolidine 
• 219562-46-6 4-[[2'-(methoxycarbonyl)methyl]oxy]-5-methoxy-2-nitrobenzoic acid 
• 679005-40-4 (11S,11aS)-8-(2-benzyloxycarbonylethoxy)-11-hydroxy-7-methoxy-5-oxo-2,3,11,11a-tetrahydro-1H,5H-pyrrolo[2,1-c][1,4]benzodiazepine-10-carboxylic acid tert-butyl ester 
• 679005-39-1 3-[5-tert-butoxycarbonylamino-4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxyphenoxy]propionic acid benzyl ester 
• 679005-37-9 3-[4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxy-5-nitrophenoxy]propionic acid benzyl ester 
• 679005-38-0 3-[5-amino-4-((2S)-2-hydroxymethylpyrrolidine-1-carbonyl)-2-methoxyphenoxy]propionic acid benzyl ester 
• 679005-36-8 4-(2-benzyloxycarbonylethoxy)-5-methoxy-2-nitrobenzoic acid 

Relevant articles and documents

Towards novel lignin-based aromatic polyesters: In-depth study of the thermal degradation and crystallization of poly(propylene vanillate)

The growing environmental concerns over the excessive emissions of greenhouse gasses and the accumulation of synthetic plastics in terrestrial and aqueous recipients have driven the public, academic and industrial awareness towards the production of novel bio-based polymeric materials. Within this frame, poly(propylene vanillate) (PPV) is an alipharomatic engineering polyester with promising thermal and mechanical properties, produced via a two-step melt polycondensation of 4-(3-hydroxypropoxy)-3-methoxybenzoic acid, a monomer derived from the potentially lignin-based vanillic acid. Herein, a systematic investigation of the non-isothermal crystallization, the thermal stability and the decomposition mechanism of PPV was performed, with the implementation of differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and pyrolysis-gas chromatography/mass spectroscopy (Py-GC/MS), respectively. The Lauritzen-Hoffman parameters (K and U*) of crystallization were calculated using a combination of the Lauritzen-Hoffman theory and isoconversional methods. The determination of the activation energy, using isoconversional methods, along with the model fitting analysis of mass loss data have led to a first assumption about the thermal degradation profile of the synthesized polyester. Furthermore, decomposition products revealed the two different main degradation mechanisms take place: heterolytic β-hydrogen scission and α-homolytic scission.

Synthesis and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 cyclic amine conjugates

We report examples of a series of novel pyrrolo[2,1-c][1,4]benzodiazepine (PBD) analogues 12-15 prepared from a common functionalized building block 11 that can be conveniently synthesized on a large scale and in optically pure form. Isoindoline analogue

Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1,4] benzodiazepine and minor-groove-binding oligopyrrole carriers

The synthesis, biological activity, and DNA-binding properties of a series of four hybrids prepared by combining polypyrrole minor groove binders and pyrrolo[2,1-c][1,4]benzodiazepine (PBD) 13, related to the naturally occurring anthramycin (3) and DC-81