1000591-93-4Relevant academic research and scientific papers
Synthesis of novel phytosphingosine derivatives and their preliminary biological evaluation for enhancing radiation therapy
Moon, Byung Seok,Park, Moon-Taek,Park, Jeong Hoon,Kim, Sang Wook,Lee, Kyo Chul,An, Gwang Il,Yang, Seung Dae,Chi, Dae Yoon,Cheon, Gi Jeong,Lee, Su-Jae
, p. 6643 - 6646 (2007)
Eight d-ribo-phytosphingosine derivatives were synthesized from d-ribo-phytosphingosine and diverse acyl chlorides with N,N-diisopropylethylamine in tetrahydrofuran for 1 h at room temperature. Effect of these compounds on IR-induced cell death was evaluated on blood cancer cells (Jurkat). Among these, 3d showed the highest enhancement of radiosensitizing effect.
