10006-90-3

Basic information

• Product Name: α,α-dimethylindole-3-ethanol
• CAS NO: 10006-90-3
• Molecular Weight: 189.257
• Mol File: 10006-90-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: α,α-dimethylindole-3-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-dimethylindole-3-ethanol(10006-90-3)
• EPA Substance Registry System: α,α-dimethylindole-3-ethanol(10006-90-3)

Safety Data

• Hazardous Substances Data: 10006-90-3(Hazardous Substances Data)

Usage

General Description

α,α-dimethylindole-3-ethanol is a chemical compound that belongs to the indole family. It is a derivative of indole with two methyl groups attached to the alpha carbon atom. α,α-dimethylindole-3-ethanol is commonly used in the pharmaceutical industry for its potential therapeutic applications. It is known for its ability to act as a selective serotonin receptor antagonist, making it a promising candidate for the treatment of various psychiatric disorders. Additionally, α,α-dimethylindole-3-ethanol has also been studied for its antioxidant properties, which could have potential benefits for overall health and wellness. Overall, this compound shows promise for various medical and pharmaceutical applications.

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 120-72-9 indole 
• 75-16-1 methylmagnesium bromide 
• 10006-89-0 2-indol-3-yl-2-methyl-propan-1-ol 
• 558-30-5 2-methyl-1,2-epoxypropane 
• 10468-64-1 o-tolyl isocyanide 
• 778-82-5 ethyl 3-indoleacetate 

Relevant articles and documents

A Cooperative Hydrogen Bond Donor–Br?nsted Acid System for the Enantioselective Synthesis of Tetrahydropyrans

Carbocations stabilized by adjacent oxygen atoms are useful reactive intermediates involved in fundamental chemical transformations. These oxocarbenium ions typically lack sufficient electron density to engage established chiral Br?nsted or Lewis acid catalysts, presenting a major challenge to their widespread application in asymmetric catalysis. Leading methods for selectivity operate primarily through electrostatic pairing between the oxocarbenium ion and a chiral counterion. A general approach to new enantioselective transformations of oxocarbenium ions requires novel strategies that address the weak binding capabilities of these intermediates. We demonstrate herein a novel cooperative catalysis system for selective reactions with oxocarbenium ions. This new strategy has been applied to a highly selective and rapid oxa-Pictet–Spengler reaction and highlights a powerful combination of an achiral hydrogen bond donor with a chiral Br?nsted acid.

Studies in the Synthesis of Brevianamides A and B: Pilot Investigations and the Preparation of 1,1-Dimethyl-1,2,4,9-tetrahydrocarbazol-3-one

In preliminary investigations directed ultimately at the synthesis of the indoxyl mould metabolites, brevianamides A and B, routes to the synthesis of 4,4-dimethyl-1,3,4,9-tetrahydrocarbazol-2-one and 1,1-dimethyl-1,2,4,9-tetrahydrocarbazol-3-one have bee