1000609-88-0

Basic information

• Product Name: ((3aR,4R,6aR)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylbenzoate
• Synonyms: ((3aR,4R,6aR)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylbenzoate
• CAS NO: 1000609-88-0
• Molecular Weight: 294.304
• Mol File: 1000609-88-0.mol

Chemical Properties

• CAS DataBase Reference: ((3aR,4R,6aR)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ((3aR,4R,6aR)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylbenzoate(1000609-88-0)
• EPA Substance Registry System: ((3aR,4R,6aR)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylbenzoate(1000609-88-0)

Safety Data

• Hazardous Substances Data: 1000609-88-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
((3aR,4R,6aR)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylbenzoate is used as a valuable intermediate for the synthesis of other organic molecules due to its unique structure and potential applications in the development of new drugs or materials with useful properties. Its hydroxyl group allows for various synthetic transformations, making it a promising candidate for further research and development in the pharmaceutical field.

Upstream product

• 131303-93-0 6-O-benzoyl-2,3-O-isopropylidine-D-ribonolactone 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 98-88-4 benzoyl chloride 
• 67814-68-0 2,3-O-isopropylidene-β-D-ribofuranose 

Downstream Products

• 116285-59-7 2-(5-O-benzoyl-2,3-O-isopropylidene-D-ribofuranosyl)-N-ethylmaleimide 
• 116285-58-6 4-(5-O-benzoyl-2,3-O-isopropylidene-D-ribofuranosyl)-1,3-dioxolan-2-one 
• 116285-54-2 5-O-benzoyl-2,3-O-isopropylidene-1S-(methylthio)carbonyl-1-thio-β-D-ribofuranose 
• 116347-70-7 1,4-anhydro-5-O-benzoyl-2,3-O-isopropylidene-D-ribitol 
• 4099-85-8 ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 
• 116306-26-4 5-O-benzoyl-2,3-O-isopropylidene-1-O-methylthiothiocarbonyl-β-D-ribofuranose 

Relevant articles and documents

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Synthesis and biological evaluation of novel apio nucleosides with thiazole-4-carboxamide and 1,2,4-triazole-3-carboxamide

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Reduction of sugar lactones to hemiacetals with lithium triethylborohydride

Reduction of ribono-1,4-lactones and gulono-1,4-lactone as well as ribono-1,5-lactone and glucono-1,5-lactones with LTBH (1.2 equiv.) in CH2Cl2at 0 °C for 30 min provided the corresponding pentose or hexose hemiacetals in high yields. Commonly used in carbohydrate chemistry protecting groups such as trityl, benzyl, silyl, acetals and to some extent acyls are compatible with this reduction.

Cobalt-catalyzed diastereoselective synthesis of C-furanosides. total synthesis of (-)-isoaltholactone

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A mild, stereoselective, and quick approach to accessing alkynyl and alkenyl C-glycosides via BF3?Et2O promoted coupling of organotrifluoroborates and glycosyl fluorides is reported. The application of this method was further demonstrated by the concise and efficient total synthesis of (+)-varitriol in only seven steps.

One-pot synthesis of acyclic nucleosides from carbohydrate derivatives, by combination of tandem and sequential reactions

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