1000698-88-3

Basic information

• Product Name: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate
• Synonyms: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate;(2-Amino-4,5-difluoro-phenyl)-carbamic acid tert-butyl ester
• CAS NO: 1000698-88-3
• Molecular Formula: C₁₁H₁₄F₂N₂O₂
• Molecular Weight: 244.2378664
• Mol File: 1000698-88-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate(1000698-88-3)
• EPA Substance Registry System: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate(1000698-88-3)

Safety Data

• Hazardous Substances Data: 1000698-88-3(Hazardous Substances Data)

Usage

General Description

Tert-Butyl (2-amino-4,5-difluorophenyl)carbamate is a chemical compound that is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is a derivative of tert-butyl carbamate and contains a substituted phenyl ring with two fluorine atoms. tert-Butyl (2-amino-4,5-difluorophenyl)carbamate is known for its potential application as a fungicide, as well as its role in the development of new drugs and treatments. It is considered a versatile and valuable intermediate in organic synthesis, with potential uses in the fields of medicine, agriculture, and materials science.

Upstream product

• 1000698-90-7 tert-butyl 4,5-difluoro-2-nitrophenylcarbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 76179-40-3 2-amino-4,5-difluoroaniline 
• 78056-39-0 4,5-difluoro-2-nitroaniline 

Downstream Products

• 1153859-80-3 2-[2-(3-Chloro-benzyl)-5,6-difluoro-benzoimidazol-1-yl]-2,N-dicyclohexyl-acetamide 
• 1162675-51-5 N-benzyl-2-cyclohexyl-2-[2-(2,6-dimethoxy-pyridin-3-yl)-5,6-difluoro-benzoimidazol-1-yl]-acetamide 
• 1162676-15-4 4-{2-cyclohexyl-2-[5,6-difluoro-2-(4-trifluoromethyl-phenyl)-benzoimidazol-1-yl]-acetylamino}-benzoic acid ethyl ester 
• 1265885-62-8 N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide 
• 1265885-42-4 N-benzyl-2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-(4,4-difluoro-cyclohexyl)-acetamide 
• 1265885-28-6 N-benzyl-2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclopentyl-acetamide 
• 1265885-23-1 N-benzyl-2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclopropyl-acetamide 

Relevant articles and documents

NEW BENZIMIDAZOLE DERIVATIVES

The invention is concerned with novel benzimidazole derivatives of Formula (I) wherein A, n and R1 to R7 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds act on Farnesyl X receptor (FXR) and against cholesterol and lipid illnesses, diabetes, obesity, psoriasis, cancer, osteoporosis, Parkinson's and Alzheimer's disease.

CARBOXYL- OR HYDROXYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.

SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 and X are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. T