100074-43-9

Basic information

• Product Name: 3-(4-chlorophenyl)-4-hydroxyfuran-2(5H)-one
• Synonyms: 3-(4-chlorophenyl)-4-hydroxyfuran-2(5H)-one
• CAS NO: 100074-43-9
• Molecular Weight: 210.617
• Mol File: 100074-43-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 3-(4-chlorophenyl)-4-hydroxyfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-4-hydroxyfuran-2(5H)-one(100074-43-9)
• EPA Substance Registry System: 3-(4-chlorophenyl)-4-hydroxyfuran-2(5H)-one(100074-43-9)

Safety Data

• Hazardous Substances Data: 100074-43-9(Hazardous Substances Data)

Upstream product

• 100074-30-4 phenylacetic acid 
• 25307-03-3 4-chlorophenylacetic acid sodium salt 
• 96-35-5 glycolic acid methyl ester 
• 52449-43-1 (4-chloro-phenyl)-acetic acid methyl ester 
• 1878-66-6 4-chlorophenylacetic Acid 

Downstream Products

• 1514777-29-7 7-(4-(2-(3-(4-chlorophenyl)furan-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1514777-31-1 7-(4-(2-(3-(4-chlorophenyl)furan-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-(4-fluorophenyl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1514777-36-6 7-(4-(2-(3-(4-chlorophenyl)furan-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 
• 1514777-27-5 7-(4-(2-(3-(4-chlorophenyl)furan-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1450824-59-5 4-(2-(4-fluorophenylacetyloxy)ethoxy)-3-(4-chlorophenyl)furan-2(5H)-one 
• 1450824-58-4 4-(2-(4-hydroxyphenylacetyloxy)ethoxy)-3-(4-chlorophenyl)furan-2(5H)-one 
• 1450824-56-2 4-(2-(3-chlorophenylacetyloxy)ethoxy)-3-(4-chlorophenyl)furan-2(5H)-one 
• 1421237-26-4 C₂₂H₁₉ClFNO₄ 
• 1421237-27-5 C₂₂H₁₉ClFNO₄ 
• 1421237-09-3 C₂₂H₂₁ClFNO₅ 
• 1339962-12-7 3-(4-chlorophenyl)-4-(3-chlorophenylamino)furan-2(5H)-one 
• 1320275-79-3 C₁₂H₁₀BrClO₃ 
• 1320275-63-5 3-(4-chlorophenyl)-4-(2-morpholinoethoxy)furan-2(5H)-one 

Relevant articles and documents

Compound, as well as preparation method and application thereof

The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.

Synthesis, molecular docking and biological evaluation of 3-arylfuran-2(5H)-ones as anti-gastric ulcer agent

3-Arylfuran-2(5H)-one derivatives show good antibacterial activity and were determined as tyrosyl-tRNA synthetase (TyrRS) inhibitors. In a systematic medicinal chemistry exploration, we demonstrated chemical opportunities to treat infections caused by Hel

A facile synthesis, antibacterial activity of pulvinone and its derivatives

Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia col