100074-44-0Relevant articles and documents
Compound, as well as preparation method and application thereof
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Paragraph 0307-0311, (2020/03/17)
The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.
Synthesis, molecular docking and biological evaluation of 3-arylfuran-2(5H)-ones as anti-gastric ulcer agent
Wang, Xu-Dong,Wei, Wei,Wang, Peng-Fei,Yi, Li-Cheng,Shi, Wei-Kang,Xie, Yong-Xiang,Wu, Lang-Zhou,Tang, Nian,Zhu, Liang-Song,Peng, Jia,Liu, Chan,Li, Xian-Hui,Tang, Shi,Xiao, Zhu-Ping,Zhu, Hai-Liang
, p. 4860 - 4865 (2015/08/03)
3-Arylfuran-2(5H)-one derivatives show good antibacterial activity and were determined as tyrosyl-tRNA synthetase (TyrRS) inhibitors. In a systematic medicinal chemistry exploration, we demonstrated chemical opportunities to treat infections caused by Hel
Synthesis of (E)- and (Z)-Pulvinones
Campbell, Alexander C.,Maidment, Maurice S.,Pick, John H.,Stevenson, Donald F. M.
, p. 1567 - 1576 (2007/10/02)
Two new routes to pulvinones have been developed, one of which involves a novel Wittig reaction.For the first time, members of the E-series, including the parent (E)-pulvinone, are reported and the structural elucidation of the geometric isomers is descri