100074-48-4Relevant articles and documents
4-Alkoxy-3-arylfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: Synthesis, molecular docking and antibacterial evaluation
Xiao, Zhu-Ping,Ouyang, Hui,Wang, Xu-Dong,Lv, Peng-Cheng,Huang, Ze-Jun,Yu, She-Rong,Yi, Tian-Fang,Yang, Ye-Ling,Zhu, Hai-Liang
, p. 3884 - 3891 (2011/08/02)
A series of novel 4-alkoxy-3-arylfuran-2(5H)-ones as tyrosyl-tRNA synthetase inhibitors were synthesized. Of these compounds, 3-(4-hydroxyphenyl)- 4-(2-morpholinoethoxy)furan-2(5H)-one (27) was the most potent. The binding model and structure-activity rel
Synthesis of (E)- and (Z)-Pulvinones
Campbell, Alexander C.,Maidment, Maurice S.,Pick, John H.,Stevenson, Donald F. M.
, p. 1567 - 1576 (2007/10/02)
Two new routes to pulvinones have been developed, one of which involves a novel Wittig reaction.For the first time, members of the E-series, including the parent (E)-pulvinone, are reported and the structural elucidation of the geometric isomers is descri