1000774-85-5Relevant academic research and scientific papers
Selective synthesis of either isoindole- or isoindoline-1-carboxylic acid esters by Pd(0)-catalyzed enolate arylation
Sole, Daniel,Serrano, Olga
experimental part, p. 6267 - 6270 (2010/12/19)
Figure presented. Two efficient palladium-catalyzed intramolecular α-arylation reactions of α-amino acid esters have been developed that allow either 1-isoindolecarboxylic acid esters or the corresponding isoindolines to be selectively synthesized simply by a slight change of reaction conditions.
Palladium-catalysed synthesis of 1-isoindolecarboxylic acid esters and sequential Diels-Alder reactions: Access to bridged- and fused-ring heterocycles
Sole, Daniel,Serrano, Olga
supporting information; experimental part, p. 3382 - 3384 (2010/01/06)
The Pd-catalysed intramolecular α-arylation of α-amino acid esters provides a useful methodology for the synthesis of substituted isoindole derivatives, which have been used in Diels-Alder reactions to access diverse skeletal frameworks.
Sequential copper(I)-catalyzed reaction of amines with o-acetylenyl- substituted phenyldiazoacetates
Peng, Cheng,Cheng, Jiajia,Wang, Jianbo
scheme or table, p. 2359 - 2364 (2009/10/20)
A highly efficient, tetrakis(acetonitrile)-copper(I) hexafluorophosphate [Cu(MeCN)4PF6]-catalyzed tandem Cu(I)-carbene N-H insertion/Cu(I)-catalyzed hydroamination of alkynes, which leads to sequential formation of two C-N bonds to yield isoindole derivatives, has been developed.
