1011458-25-5

Basic information

• Product Name: methyl 2-diazo-2-(2-ethynylphenyl)acetate
• Synonyms: methyl 2-diazo-2-(2-ethynylphenyl)acetate
• CAS NO: 1011458-25-5
• Molecular Weight: 200.197
• Mol File: 1011458-25-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-diazo-2-(2-ethynylphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-diazo-2-(2-ethynylphenyl)acetate(1011458-25-5)
• EPA Substance Registry System: methyl 2-diazo-2-(2-ethynylphenyl)acetate(1011458-25-5)

Safety Data

• Hazardous Substances Data: 1011458-25-5(Hazardous Substances Data)

Upstream product

• 799804-49-2 (2-trimethylsilanylethynyl-phenyl)-acetic acid methyl ester 
• 66370-75-0 methyl (2-iodophenyl)acetate 
• 103-82-2 phenylacetic acid 
• 18698-96-9 o-iodophenylacetic acid 
• 637348-19-7 (2-ethynylphenyl)acetic acid methyl ester 

Downstream Products

• 1000774-82-2 methyl 3-methyl-2-p-tolyl-2H-isoindole-1-carboxylate 
• 1000774-85-5 methyl 2-(4-methoxyphenyl)-3-methyl-2H-isoindole-1-carboxylate 
• 1000774-84-4 methyl 3-methyl-2-(4-nitrophenyl)-2H-isoindole-1-carboxylate 
• 1000774-81-1 methyl 3-methyl-2-phenyl-2H-isoindole-1-carboxylate 
• 1000774-83-3 methyl 2-(3,4-dichlorophenyl)-3-methyl-2H-isoindole-1-carboxylate 
• 1160367-29-2 methyl 2-benzyl-3-methyl-2H-isoindole-1-carboxylate 
• 1000774-86-6 methyl 2-(4-bromophenyl)-3-methyl-2H-isoindole-1-carboxylate 

Relevant articles and documents

Gold-catalyzed intermolecular [4+1] spiroannulation: via site-selective aromatic C(sp2)-H functionalization and dearomatization of phenol derivatives

Herein, we have developed a novel and simple protocol to realize the C-H bond functionalization/dearomatization of naphthols and phenols with ortho-alkynylaryl-α-diazoesters under gold(i) catalysis. In this protocol, various spirocyclic molecules could be obtained in good yields with excellent chemo- and regio-selectivity and moderate to good diastereoselectivity. This journal is