1000790-76-0Relevant academic research and scientific papers
Clarification of the role of water in proline-mediated aldol reactions
Zotova, Natalia,Franzke, Axel,Armstrong, Alan,Blackmond, Donna G.
, p. 15100 - 15101 (2007)
A coherent mechanistic rationalization of the role of water in aldol reactions employing aromatic aldehydes shows that the intrinsic kinetic effect of water within the catalytic cycle is a suppression of reaction rate. The presence of water suppresses for
