1000860-21-8

Basic information

• Product Name: 5,7-dichloro-3-(4-chlorobenzyl)quinazoline-2,4(1H,3H)-dione
• Synonyms: 5,7-dichloro-3-(4-chlorobenzyl)quinazoline-2,4(1H,3H)-dione
• CAS NO: 1000860-21-8
• Molecular Weight: 355.608
• Mol File: 1000860-21-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5,7-dichloro-3-(4-chlorobenzyl)quinazoline-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-dichloro-3-(4-chlorobenzyl)quinazoline-2,4(1H,3H)-dione(1000860-21-8)
• EPA Substance Registry System: 5,7-dichloro-3-(4-chlorobenzyl)quinazoline-2,4(1H,3H)-dione(1000860-21-8)

Safety Data

• Hazardous Substances Data: 1000860-21-8(Hazardous Substances Data)

Upstream product

• 20776-63-0 2-amino-4,6-dichlorobenzoic acid 
• 104-86-9 4-chlorobenzylamine 
• 1000859-37-9 2-amino-4,6-dichloro-N-(4-chlorobenzyl)benzamide 

Relevant articles and documents

PHARMACOLOGICALLY ACTIVE QUINAZOLINEDIONE DERIVATIVES

Compounds of formula (I), wherein R1-8 are as defined in the claims, exhibit a positive allosteric GABAB modulator effect and are thus useful as positive allosteric modulators of the GABAB receptor.

NOVEL SUBSTITUTED-1H-QUINAZOLINE-2,4-DIONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Disclosed herein are novel substituted-lH-quinazoline-2,4-dione derivatives, a preparation method thereof, and a pharmaceutical composition containing the same. The novel substituted- lH-quinazoline-2,4-dione derivatives are excellent in binding affinity