1000890-53-8 Usage
Description
2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester, with the CAS number 1000890-53-8, is a white solid compound that plays a significant role in organic synthesis. It is a derivative of neuraminic acid, a key component of various biological molecules, and features a p-nitrophenyl group attached to the 2-O position, which imparts unique chemical properties to the molecule.
Uses
Used in Organic Synthesis:
2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester is used as a synthetic intermediate for the preparation of various complex organic molecules. Its unique structure allows for selective reactions and modifications, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research and Development:
In the field of research and development, 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester serves as a valuable tool for studying the structure, function, and interactions of neuraminic acid-containing biomolecules. Its p-nitrophenyl group can be used as a reporter or probe to monitor the progress of chemical reactions or to investigate the binding properties of enzymes and other proteins.
Used in Pharmaceutical Industry:
2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester is used as a key component in the development of new drugs targeting various diseases. Its unique structure and reactivity make it an attractive candidate for the design of novel therapeutic agents, particularly in the areas of infectious diseases, cancer, and neurological disorders.
Used in Analytical Chemistry:
In analytical chemistry, 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester can be employed as a reference compound or standard for the development and validation of analytical methods. Its distinct chemical properties and reactivity make it suitable for use in high-performance liquid chromatography (HPLC), mass spectrometry, and other analytical techniques.
Overall, 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester is a versatile and valuable compound with a wide range of applications in various industries, including organic synthesis, research and development, pharmaceuticals, and analytical chemistry. Its unique structure and properties make it an essential tool for the advancement of scientific knowledge and the development of innovative products.
Check Digit Verification of cas no
The CAS Registry Mumber 1000890-53-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,8,9 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1000890-53:
(9*1)+(8*0)+(7*0)+(6*0)+(5*8)+(4*9)+(3*0)+(2*5)+(1*3)=98
98 % 10 = 8
So 1000890-53-8 is a valid CAS Registry Number.
1000890-53-8Relevant articles and documents
Transsialidase from Trypanosoma cruzi for regio- and stereoselective synthesis of N-acyl-modified sialylated oligosaccharides and measurement of transfer rates
Schroven, Andreas,Meinke, Sebastian,Ziegelmueller, Patrick,Thiem, Joachim
, p. 9012 - 9021 (2008/09/16)
Recombinant transsialidase from Trypanosoma cruzi (TcTS) was used for the sialylation with natural and non-natural derivatives of neuraminic acid. Neu5Ac-α(2→3)-Gal-β(1→6)-Glc-αOMe was prepared in 80% yield. Correspondingly, the modified trisaccharide derivatives Neu5Prop-α(2 →3)-Gal-β(1 →6)-GlcαOMe (32%) and Neu5Gc-α(2→3)-Gal-β(1→6)-Glc-αOMe (Prop = propanoyl, Gc = glycolyl) were obtained in 60 % yield, respectively.
