1000890-36-7

Basic information

• Product Name: 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid
• Synonyms: 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid;Glycoylyl5Ac2-α-PNP;N-(2-Hydroxyacetyl)-2-O-(4-nitrophenyl)-α-neuraMinic Acid;N-(2-Hydroxyacetyl)-2-O-(4-nitrophenyl)-alpha-neuraminic acid
• CAS NO: 1000890-36-7
• Molecular Formula: C₁₇H₂₂N₂O₁₂
• Molecular Weight: 446.36278
• Product Categories: 13C & 2H Sugars;Carbohydrates & Derivatives
• Mol File: 1000890-36-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 148-150°C
• Appearance: /
• Storage Temp.: -20?C Freezer
• Solubility: Methanol, Water
• CAS DataBase Reference: 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid(1000890-36-7)
• EPA Substance Registry System: 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid(1000890-36-7)

Safety Data

• Hazardous Substances Data: 1000890-36-7(Hazardous Substances Data)

Usage

Description

2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid, with the CAS number 1000890-36-7, is a pale yellow solid compound that plays a significant role in organic synthesis. It is a derivative of neuraminic acid, a key component of various biological molecules, and has unique chemical properties that make it valuable in the synthesis of complex organic compounds.

Uses

Used in Organic Synthesis:
2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid is used as a key intermediate in the synthesis of complex organic compounds. Its unique chemical properties allow for the formation of various derivatives and analogs, which can be further utilized in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid is used as a building block for the development of novel drug candidates. Its ability to form various derivatives makes it a versatile component in the design and synthesis of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid is also used in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its unique chemical properties enable the development of innovative compounds with improved efficacy and selectivity.
Used in Research and Development:
In the field of research and development, 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid serves as a valuable tool for studying the structure and function of various biological molecules. Its unique properties allow researchers to probe the interactions between different biomolecules and gain insights into their mechanisms of action.
Overall, 2-O-(p-Nitrophenyl)-α-D-N-glycolylneuraminic Acid is a versatile compound with a wide range of applications across various industries, including organic synthesis, pharmaceuticals, agrochemicals, and research and development. Its unique chemical properties and potential for further modification make it an essential component in the development of innovative products and solutions.

Upstream product

• 1000890-53-8 C₁₈H₂₄N₂O₁₂ 

Downstream Products

• 100-02-7 4-nitro-phenol 
• 1000890-57-2 C₂₄H₄₁NO₂₀ 

Relevant articles and documents

Transsialidase from Trypanosoma cruzi for regio- and stereoselective synthesis of N-acyl-modified sialylated oligosaccharides and measurement of transfer rates

Recombinant transsialidase from Trypanosoma cruzi (TcTS) was used for the sialylation with natural and non-natural derivatives of neuraminic acid. Neu5Ac-α(2→3)-Gal-β(1→6)-Glc-αOMe was prepared in 80% yield. Correspondingly, the modified trisaccharide derivatives Neu5Prop-α(2 →3)-Gal-β(1 →6)-GlcαOMe (32%) and Neu5Gc-α(2→3)-Gal-β(1→6)-Glc-αOMe (Prop = propanoyl, Gc = glycolyl) were obtained in 60 % yield, respectively.