1001128-48-8

Basic information

• Product Name: [7-(2,6-Difluorophenyl)-2-(tetrahydro-pyran-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-(4-fluorophenyl)-methanone
• Synonyms: [7-(2,6-Difluorophenyl)-2-(tetrahydro-pyran-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-(4-fluorophenyl)-methanone
• CAS NO: 1001128-48-8
• Molecular Weight: 452.436
• Mol File: 1001128-48-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [7-(2,6-Difluorophenyl)-2-(tetrahydro-pyran-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-(4-fluorophenyl)-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [7-(2,6-Difluorophenyl)-2-(tetrahydro-pyran-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-(4-fluorophenyl)-methanone(1001128-48-8)
• EPA Substance Registry System: [7-(2,6-Difluorophenyl)-2-(tetrahydro-pyran-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-(4-fluorophenyl)-methanone(1001128-48-8)

Safety Data

• Hazardous Substances Data: 1001128-48-8(Hazardous Substances Data)

Upstream product

• 38041-19-9 4-aminotetrahydropyran 
• 1001128-52-4 [7-(2,6-difluorophenyl)-2-methanesulfonyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-(4-fluorophenyl)-methanone 

Relevant articles and documents

Pyrrolo[2,3-d]pyrimidine cytokine inhibitors

The present invention relates to 2,6,7-substituted pyrrolo[2,3-d]pyrimidines which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 2,6,7-substituted pyrrolo[2,3-d]pyrimidines and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.