1001171-07-8

Basic information

• Product Name: C₂₅H₂₇N₇O
• CAS NO: 1001171-07-8
• Molecular Weight: 441.536
• Mol File: 1001171-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₇N₇O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₇N₇O(1001171-07-8)
• EPA Substance Registry System: C₂₅H₂₇N₇O(1001171-07-8)

Safety Data

• Hazardous Substances Data: 1001171-07-8(Hazardous Substances Data)

Upstream product

• 180741-30-4 (3-methyl-1H-pyrazol-1-yl)acetic acid 
• 1001183-82-9 C₁₉H₂₁N₅ 

Relevant articles and documents

Synthesis and in vitro activity of N′-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists

A novel series of cyanoguanidine-piperazine P2X7 antagonists was designed based upon the structure of A-740003. Structure-activity relationship (SAR) studies focused on the piperazine moiety and the right hand side substitution. Compounds were assayed for activity at human and rat P2X7 receptors and compound 29 was found to possess potent activity (IC50 = 30-60 nM) at both species.