1001208-22-5Relevant academic research and scientific papers
Evolution of the total synthesis of (-)-Okilactomycin exploiting a tandem oxy-cope rearrangement/oxidation, a petasis-ferrier union/rearrangement, and ring-closing metathesis
Smith, Amos B. III,Bosanac, Todd,Basu, Kallol
supporting information; experimental part, p. 2348 - 2358 (2009/07/30)
An effective, asymmetric total synthesis of the antitumor antibiotic (-)-okilactomycin (1), as well as assignment of the absolute configuration,has been achieved exploiting a convergent strategy. Highlights of the s ynthesis include a diastereoselective o
Total synthesis of (-)-okilactomycin
Smith III, Amos B.,Basu, Kallol,Bosanac, Todd
, p. 14872 - 14874 (2008/09/20)
A highly convergent synthesis of (-)-okilactomycin is described. Key reactions of this synthesis include a strategy-level diastereoselective oxy-Cope rearrangement/oxidation sequence, a Petasis-Ferrier union/rearrangement tactic, and an efficient RCM reac
