100121-80-0

Basic information

• Product Name: CYCLOBUTYL 4-METHOXYPHENYL KETONE
• Synonyms: CYCLOBUTYL 4-METHOXYPHENYL KETONE;UKRORGSYN-BB BBV-5119102;Methanone, cyclobutyl(4-methoxyphenyl)-
• CAS NO: 100121-80-0
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.24
• Mol File: 100121-80-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 320.3°C at 760 mmHg
• Flash Point: 145.4°C
• Appearance: /
• Density: 1.106g/cm³
• Vapor Pressure: 0.00032mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: CYCLOBUTYL 4-METHOXYPHENYL KETONE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOBUTYL 4-METHOXYPHENYL KETONE(100121-80-0)
• EPA Substance Registry System: CYCLOBUTYL 4-METHOXYPHENYL KETONE(100121-80-0)

Safety Data

• Hazardous Substances Data: 100121-80-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H14O2/c1-14-11-7-5-10(6-8-11)12(13)9-3-2-4-9/h5-9H,2-4H2,1H3

Upstream product

• 3721-95-7 Cyclobutanecarboxylic acid 
• 100-66-3 methoxybenzene 
• 5006-22-4 Cyclobutanecarbonyl chloride 

Downstream Products

• 31480-64-5 1‐(cyclobutylmethyl)‐4‐methoxybenzene 
• 108395-01-3 Cyclobutyl-(4-methoxy-phenyl)-pyrimidin-5-yl-methanol 

Relevant articles and documents

Electrochemical [4+2] Annulation-Rearrangement-Aromatization of Styrenes: Synthesis of Naphthalene Derivatives

We report the first electrochemical strategy to synthesize functionalized naphthalene derivatives through [4+2] annulation—rearrangement–aromatization from styrenes under mild conditions. The electrolysis does not require metals, oxidants and high valence substrates, indicating the atom and step-economy ideals. The dehydrodimer produced through [4+2] cycloaddition of 4-methoxy α-methyl styrene is isolated and proved to be the key intermediate for the following oxydehydrogenation to form carbon cation, which undergoes rearrangement–aromatization to afford the final products. This reaction represents a powerful access to construct multi-substituted naphthalene blocks in a single step.