100127-77-3

Basic information

• Product Name: 2-Hydroxy-2-methyl-4-phenylbutanenitrile
• Synonyms: 2-Hydroxy-2-methyl-4-phenylbutanenitrile
• CAS NO: 100127-77-3
• Molecular Weight: 175.23
• Mol File: 100127-77-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Hydroxy-2-methyl-4-phenylbutanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-2-methyl-4-phenylbutanenitrile(100127-77-3)
• EPA Substance Registry System: 2-Hydroxy-2-methyl-4-phenylbutanenitrile(100127-77-3)

Safety Data

• Hazardous Substances Data: 100127-77-3(Hazardous Substances Data)

Upstream product

• 2550-26-7 4-Phenyl-2-butanone 
• 74-90-8 hydrogen cyanide 

Downstream Products

• 1092080-74-4 (2R)-2-cyano-4-phenylbutan-2-yl (R)-2-methoxy-2-phenylacetate 
• 1092080-75-5 (2R)-2-cyano-4-phenylbutan-2-yl (S)-2-methoxy-2-phenylacetate 

Relevant articles and documents

Synthesis of Succinonitrile Derivatives by Homocoupling from Cyanohydrin Derivatives with a Low-Valent Titanium Reagent

A method is described for synthesizing succinonitrile derivatives bearing alkyl or aryl substituents from cyanohydrin derivatives using low-valent titanium. The active species in this reaction is proposed to be a resonance hybrid of the TiIV nitrile enolate and TiIII alkyl radical.