1092080-75-5Relevant academic research and scientific papers
The use of a single derivative in the configurational assignment of ketone cyanohydrins
Louzao, Iria,Seco, Jose M.,Quinoa, Emilio,Riguera, Ricardo
experimental part, p. 6520 - 6524 (2011/02/22)
The absolute stereochemistry of ketone cyanohydrins can be easily determined by preparing a single MPA derivative. The comparison of two NMR spectra at different temperatures allows the assignment by just paying attention to the evolution of the cyanohydr
13C NMR as a general tool for the assignment of absolute configuration
Louzao, Iria,Seco, Jose Manuel,Quinoa, Emilio,Riguera, Ricardo
supporting information; experimental part, p. 7903 - 7905 (2010/12/19)
13C NMR, alone or in combination with 1H NMR, allows the assignment of the absolute configuration of chiral alcohols, amines, carboxylic acids, thiols, cyanohydrins, sec,sec-diols and sec,sec-aminoalcohols, derivatized with appropriate chiral auxiliaries. This extends the assignment possibilities of NMR to fully deuterated and to nonproton containing compounds.
Absolute configuration of ketone cyanohydrins by 1H nmr: The special case of polar substituted tertiary alcohols
Louzao, Iria,Garcia, Rosa,Seco, Jose Manuel,Quinoa, Emilio,Riguera, Ricardo
supporting information; experimental part, p. 53 - 56 (2009/07/04)
The absolute configuration of ketone cyanohydrins can be assigned from analysis of the 1H NMR spectra of the corresponding (R)-and (S)-MPA ester derivatives and use of ΔδRS signs. This is an application of the NMR methodology for ste
