100134-80-3

Basic information

• Product Name: Benzoic acid, 4-(4,5-dihydro-1H-imidazol-2-yl)-, ethyl ester
• CAS NO: 100134-80-3
• Molecular Formula: C12H14N2O2
• Molecular Weight: 218.255
• Mol File: 100134-80-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(4,5-dihydro-1H-imidazol-2-yl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(4,5-dihydro-1H-imidazol-2-yl)-, ethyl ester(100134-80-3)
• EPA Substance Registry System: Benzoic acid, 4-(4,5-dihydro-1H-imidazol-2-yl)-, ethyl ester(100134-80-3)

Safety Data

• Hazardous Substances Data: 100134-80-3(Hazardous Substances Data)

Upstream product

• 7153-22-2 ethyl 4-cyanobenzoate 
• 14034-59-4 ethylene diamine mono-p-toluenesulfonic acid salt 

Downstream Products

• 175152-65-5 methyl 4-(1-methyl-1H-imidazol-2-yl)benzoate 
• 210961-91-4 4-(4,5-Dihydroimidazol-2-yl)benzoic acid hydrochloride 
• 210962-26-8 ethyl 4-(1H-imidazol-2-yl)benzoate 

Relevant articles and documents

Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase

Replacement of the dihydroquinolinone pharmacophore of Zeneca's ZD2138 by ionizable imidazolylphenyl moiety has lead to the discovery of a novel series of potent and orally active 5-lipoxygenase (5-LO) inhibitors. The synthesis and structure-activity relationship (SAR) of this series of compounds are described herein.

BENZAMIDINE DERIVATIVES

Benzamidine derivatives of the following formulae or analogs thereof, i. e., pharmaceutically acceptable salts thereof, are provided. These compounds or salts thereof have a blood-coagulation inhibiting effect based on an excellent effect of inhibiting the action of activated blood coagulation factor X, and they are useful as anticoagulants.