1001353-92-9 Usage
Uses
Used in Pharmaceutical Industry:
(R)-3-Amino-1-methyl-piperidine is used as a building block for the synthesis of various pharmaceutical compounds, particularly those with potential antitumor activity. Its unique structure allows for the creation of novel drug candidates that can target specific biological pathways involved in cancer development and progression.
Used in Anticancer Applications:
In the field of oncology, (R)-3-Amino-1-methyl-piperidine is utilized as a key component in the preparation of phthalazinone derivatives, which have demonstrated antitumor properties. These derivatives can modulate various oncological signaling pathways, potentially leading to the inhibition of tumor growth and the enhancement of the effectiveness of conventional chemotherapy.
Used in Organic Synthesis:
(R)-3-Amino-1-methyl-piperidine serves as an important intermediate in the synthesis of a wide range of organic compounds, including those with potential applications in various industries such as pharmaceuticals, agrochemicals, and materials science. Its versatility as a synthetic building block makes it a valuable asset in the development of new molecules with diverse functionalities and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1001353-92-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,3,5 and 3 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1001353-92:
(9*1)+(8*0)+(7*0)+(6*1)+(5*3)+(4*5)+(3*3)+(2*9)+(1*2)=79
79 % 10 = 9
So 1001353-92-9 is a valid CAS Registry Number.
1001353-92-9Relevant academic research and scientific papers
TROPANE COMPOUNDS
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Page/Page column 378, (2009/05/30)
A compound according to Formula I or II: (I) or (II) wherein R1, R1b, R2, L1, and L2 and L2b are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.
PYRROLOTRIAZINE KINASE INHIBITORS
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Page/Page column 72, (2011/04/19)
The invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity thereby making them useful as anticancer agents and for the treatment of Alzheimer's Disease.
PYRAZOLE DERIVATIVES FOR THE INHIBITION OF CDK' S AND GSK' S
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Page/Page column 140-141, (2008/06/13)
The invention provides compounds of the formula (I), or salts, tautomers, N-oxides or solvates thereof wherein: R1 is selected from: (a) 2,6-dichlorophenyl; (b) 2,6-difluorophenyl; (c) a 2,3,6-trisubstituted phenyl group wherein the substituents for the phenyl group are selected from fluorine, chlorine, methyl and methoxy; (d) a group R0; (e) a group R a; (f) a group Rlb; (g) a group Rlc; (h) a group Rld; and 0) 2,6-difluorophenylamino ; wherein R )0υ, r R> llaa, T Rj I1bD, T R) I1cC, r R> Iidα, r R?2zaa, r R>22bD and RJ are as defined in the claims. The compounds have activity as inhibitors of cdk kinase (such as cdkl or cdk2) and glycogen synthase kinase-3 activity.
