1001390-64-2

Upstream product

• 150444-93-2 2-chloro-3,4-difluorobenzoic acid 
• 455-86-7 3,4-Difluorobenzoic acid 
• 924626-67-5 2-chloro-3,4-difluorobenzoic acid amide 

Downstream Products

• 1069093-02-2 N-[(2-chloro-3,4-difluorophenyl)methyl]-3-methyl-1-(3-methyl-2-pyridinyl)-2-oxo-4-imidazolidinecarboxamide 
• 1071814-20-4 N-[(2-chloro-3,4-difluorophenyl)methyl]-2-(1,4-dimethyl-1H-pyrazol-5-yl)acetamide 
• 1071814-19-1 N-[(2-chloro-3,4-difluorophenyl)methyl]-2-[4-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]acetamide 

Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES AS P2X7 MODULATORS

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R1 represents C1-6 alkyl or C3-6 cycloalkyl, either of which is optionally substituted with 1, 2 or 3 ha

Novel Receptor Antagonists and Their Methods of Use

The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.