924626-67-5

Basic information

• Product Name: Benzamide, 2-chloro-3,4-difluoro-
• CAS NO: 924626-67-5
• Molecular Formula: C7H4ClF2NO
• Molecular Weight: 191.565
• Mol File: 924626-67-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-chloro-3,4-difluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-chloro-3,4-difluoro-(924626-67-5)
• EPA Substance Registry System: Benzamide, 2-chloro-3,4-difluoro-(924626-67-5)

Safety Data

• Hazardous Substances Data: 924626-67-5(Hazardous Substances Data)

Upstream product

• 455-86-7 3,4-Difluorobenzoic acid 
• 150444-93-2 2-chloro-3,4-difluorobenzoic acid 

Downstream Products

• 1001390-64-2 [(2-chloro-3,4-difluorophenyl)methyl]amine hydrochloride 
• 924626-68-6 2-chloro-3,4-difluorobenzonitrile 

Relevant articles and documents

Novel Receptor Antagonists and Their Methods of Use

The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.

CYCLIC AMINE COMPOUND

A compound represented by the formula (I) or a salt thereof: (I) wherein the ring A represents a 5- to 8-membered ring which may have additional substituent besides R6, R7 and R8; R1 represents an electron-attracting group; R2, R3, R4 and R5 independently represent a hydrogen atom, a halogen atom, a group attached through a carbon atom, a group attached through a nitrogen atom, a group attached through an oxygen group, or a group attached through a sulfur atom; R6 represents a halogen atom, a group attached through a carbon atom, a group attached through a nitrogen atom, a group attached through an oxygen group, or a group attached through a sulfur atom, and R7 represents a cyano group, a nitro group, an acyl group which may have a substituent, a carboxyl group which may be esterified or amidated, or a hydrocarbon group which may have a substituent, or R6 and R7 together with a carbon atom to which they are attached may form a ring which may have a substituent; and R8 represents a hydrogen atom, a halogen atom, a group attached through a carbon atom, a group attached through an oxygen atom, or a group attached through a sulfur atom. The compound or salt has an excellent androgen receptor modulating effect, and is useful for the prevention/treatment of hypogonadism, partial androgen deficiency in aging male, decline in physical strength, cachexia, osteoporosis and the like.