1001397-31-4 Usage
General Description
1-(5-Fluoro-pyrimidin-2-yl)-piperidin-4-ol is a chemical compound that consists of a piperidine ring with a hydroxyl group attached at the 4th position and a fluorinated pyrimidine ring at the 1st position. It is often used in pharmaceutical research and drug development due to its potential therapeutic properties. 1-(5-Fluoro-pyrimidin-2-yl)-piperidin-4-ol has been studied for its potential as a synthetic intermediate in the production of medications targeting various diseases and conditions. Additionally, it has been explored for its potential as a pharmacological tool in the study of the nervous system and other biological processes. The chemical structure and properties of 1-(5-Fluoro-pyrimidin-2-yl)-piperidin-4-ol make it a promising candidate for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1001397-31-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,3,9 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1001397-31:
(9*1)+(8*0)+(7*0)+(6*1)+(5*3)+(4*9)+(3*7)+(2*3)+(1*1)=94
94 % 10 = 4
So 1001397-31-4 is a valid CAS Registry Number.
1001397-31-4Relevant articles and documents
Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists
Katamreddy, Subba R.,Carpenter, Andrew J.,Ammala, Carina E.,Boros, Eric E.,Brashear, Ron L.,Briscoe, Celia P.,Bullard, Sarah R.,Caldwell, Richard D.,Conlee, Christopher R.,Croom, Dallas K.,Hart, Shane M.,Heyer, Dennis O.,Johnson, Paul R.,Kashatus, Jennifer A.,Minick, Doug J.,Peckham, Gregory E.,Ross, Sean A.,Roller, Shane G.,Samano, Vicente A.,Sauls, Howard R.,Tadepalli, Sarva M.,Thompson, James B.,Xu, Yun,Way, James M.
, p. 10972 - 10994 (2013/02/25)
GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119