100141-43-3 Usage
General Description
CHEMBRDG-BB 7246527 is a chemical compound with the molecular formula C23H28N2O6. It is a peptide derivative containing an anthranilic acid moiety and is classified as a benzene and substituted pyrrolidine derivative. This chemical has shown activity as an inhibitor of carbonic anhydrase IX, which is a protein that is overexpressed in many solid tumors. It has potential applications in the development of anticancer drugs targeting this protein. However, further research is needed to fully understand its biological and pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 100141-43-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,1,4 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 100141-43:
(8*1)+(7*0)+(6*0)+(5*1)+(4*4)+(3*1)+(2*4)+(1*3)=43
43 % 10 = 3
So 100141-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H16ClNO/c1-8-6-9(2)12(10(3)7-8)14-11(15)4-5-13/h6-7H,4-5H2,1-3H3,(H,14,15)
100141-43-3Relevant articles and documents
Modular synthesis of heterocyclic carbene precursors
Paczal, Attila,Benyei, Attila C.,Kotschy, Andras
, p. 5969 - 5979 (2007/10/03)
A series of N-heterocyclic carbene precursors, containing an imidazoline or tetrahydropyrimidine framework, were prepared from ω-chloroalkanoyl chlorides. The sequential attachment of nitrogen nucleophiles and subsequent ring closure gave, depending on the reagents used, either the desired dihydroimidazolium and tetrahydropyrimidinium salts or their parent heterocycles. In this latter case, the second substituent was introduced in an alkylation step. The preparation of carbene precursors bearing chiral or bulky substituents was achieved with comparable efficiency.
