1001525-91-2

Basic information

• Product Name: 1-methylcyclopropanecarboxylic acid benzyl ester
• Synonyms: 1-methylcyclopropanecarboxylic acid benzyl ester
• CAS NO: 1001525-91-2
• Molecular Weight: 190.242
• Mol File: 1001525-91-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methylcyclopropanecarboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylcyclopropanecarboxylic acid benzyl ester(1001525-91-2)
• EPA Substance Registry System: 1-methylcyclopropanecarboxylic acid benzyl ester(1001525-91-2)

Safety Data

• Hazardous Substances Data: 1001525-91-2(Hazardous Substances Data)

Upstream product

• 6914-76-7 1-Methyl-cyclopropanoic acid 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Cyclopropanecarboxylic acid esters as potential prodrugs with enhanced hydrolytic stability

Esters of cyclopropanecarboxylic acid demonstrate a substantial increase in stability under both acid- and base-catalyzed hydrolytic conditions. Comparison of the stability of valacyclovir 13 with the cyclopropane analogue 14 shows that at 40 °C and pH 6 the half-life of 14 is >300 h while the value for 13 is 69.7 h. CBS-QB3 calculations on isodesmic reactions for transfer of groups from an alkane to an ester show that a cyclopropyl group provides hyperconjugative stabilization.