100157-54-8

Basic information

• Product Name: Z-D-aThr(t-Bu)-OMe
• Synonyms: Z-D-aThr(t-Bu)-OMe
• CAS NO: 100157-54-8
• Molecular Weight: 323.389
• Mol File: 100157-54-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Z-D-aThr(t-Bu)-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-aThr(t-Bu)-OMe(100157-54-8)
• EPA Substance Registry System: Z-D-aThr(t-Bu)-OMe(100157-54-8)

Safety Data

• Hazardous Substances Data: 100157-54-8(Hazardous Substances Data)

Upstream product

• 57224-63-2 Z-DL-aThr-OMe 
• 115-11-7 isobutene 
• 501-53-1 benzyl chloroformate 
• 57224-63-2 Z-DL-Thr-OMe 
• 100157-53-7 N-carbobenzyloxy-D-allo-threonine methyl ester 
• 16966-09-9 N-Z-O-tert-butyl-L-threonine 
• 74-88-4 methyl iodide 

Downstream Products

• 42417-73-2 Z-N-Me-DL-aThr(t-Bu)-OH 
• 42417-73-2 Z-N-Me-DL-Thr(t-Bu)-OH 
• 100157-56-0 Z-N-Me-D-aThr(tBu)-OH 
• 100157-59-3 Z-N-Me-D-aThr(tBu)-L-Arg(NO₂)-OMe 
• 16966-09-9 Z-DL-aThr(t-Bu)-OH 
• 16966-09-9 Z-DL-Thr(t-Bu)-OH 
• 100157-55-9 Z-D-aThr(t-Bu)-OH 

Relevant articles and documents

1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS

The present invention relates to 1,2,4-oxadiazole compounds of formula (I) and their use to inhibit the programmed cell death (PD1) signaling pathway and/or for treatment of disorders by inhibiting an immunosuppressive signal induced by PD-1,PD-L1 or PD-L2.