1001847-93-3Relevant academic research and scientific papers
One-Pot Copper-Catalyzed Cascade Bicyclization Strategy for Synthesis of 2-(1H-Indol-1-yl)-4,5-dihydrothiazoles and 2-(1H-Indol-1-yl)thiazol-5-yl Aryl Ketones with Molecular Oxygen as an Oxygen Source
Xie, Jialin,Guo, Zhonglin,Huang, Yuanqiong,Qu, Yi,Song, Hongjian,Song, Haibin,Liu, Yuxiu,Wang, Qingmin
supporting information, p. 490 - 495 (2019/01/04)
An atom-economical method for synthesizing N-heterocyclic indoles from readily available o-alkynylphenyl isothiocyanates and propargylamine derivatives is reported. This method involves a copper-catalyzed cascade bicyclization process consisting of an int
Double three bromo 1,3-di-pyridine salt-based propane and its preparation method, method of use, recovery method and application
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Paragraph 0075; 0076; 0130; 0131, (2016/10/07)
The invention discloses a double tribromo 1,3-bipyridine onium salt dimethylmethane, and a preparation method, an application method, a recovery method and application thereof. The preparation method comprises the following steps: dissolving 1,3-bipyridine onium salt dimethylmethane by using water, and then adding potassium bromide; adding potassium peroxymonosulfate sulfate compound brine solution to prepare a clear solution after dissolving potassium bromide, and then stirring and reacting at -10 to 0 DEG C until solid is separated out; separating out solid, so as to obtain the double tribromo 1,3-bipyridine onium salt dimethylmethane. The product can be used for preparing isothiocyanate, aromatic thiourea or acetanilide. The preparation method disclosed by the invention is mild in condition, and simple to operate the reaction process, and raw materials are easily available. The double tribromo 1,3-bipyridine onium salt dimethylmethane not only can be used as a brominating reagent, but also can be used as organic synthesis intermediates, meanwhile, the reaction efficiency is improved, and the double tribromo 1,3-bipyridine onium salt dimethylmethane is convenient to recover and can be recycled.
TfOH-promoted transformation from 2-alkynylphenyl isothiocyanates to quinoline-2-thiones or indoles
Otani, Takashi,Kunimatsu, Shinichi,Takahashi, Taku,Nihei, Hiroshi,Saito, Takao
supporting information; body text, p. 3853 - 3856 (2009/10/11)
A variety of 4-arylquinoline-2-thiones and 3-arylthieno[2,3-b]indoles were synthesized in high yields via TfOH-promoted tandem Friedel-Crafts alkenylation-cyclization reactions of 2-alkynylphenyl isothiocyanates.
Synthesis of quinoline-2-thiones via tandem indium(III)-promoted friedel-crafts alkenylation-cyclization of 2-alkynylphenyl isothiocyanates
Otani, Takashi,Kunimatsu, Shinichi,Nihei, Hiroshi,Abe, Yuko,Saito, Takao
, p. 5513 - 5516 (2008/09/17)
A new approach to the synthesis of 4-aryl- or 4-arylthioquinoline-2-thiones via indium(III) reagent-mediated tandem Friedel-Crafts alkenylation-cyclization of 2-alkynylphenyl isothiocyanates is described.
