1001852-28-3Relevant articles and documents
A facile synthesis of p- and m-(amidinomethyl)phenyl esters derived from amino acid and tryptic hydrolysis of these synthetic inverse substrates
Sekizaki, Haruo,Itoh, Kunihiko,Shibuya, Akiyoshi,Toyota, Eiko,Tanizawa, Kazutaka
, p. 1514 - 1517 (2008/03/12)
A facile synthetic method for p- and m-(amidinomethyl)phenyl esters derived from a variety of amino acids is presented. We analyzed the kinetic behavior of trypsin towards these synthetic esters, which are inverse substrates. The substituent (meta- and para-isomers) and isosteric effects of (amidinomethyl)phenyl esters are discussed.