1001909-35-8Relevant academic research and scientific papers
Synthesis and structure-activity relationships of novel 2',2'-difluoro analogues of docetaxel
Uoto, Kouichi,Ohsuki, Satoru,Takenoshita, Haruhiro,Ishiyama, Takashi,Iimura, Shin,Hirota, Yasuhide,Mitsui, Ikuo,Terasawa, Hirofumi,Soga, Tsunehiko
, p. 1793 - 1804 (1997)
To investigate the role of the 2'-hydroxy group at the C-13 side chain of docetaxel in the antitumor activity, we prepared several 2',2'-difluoro derivatives of docetaxel and evaluated their cytotoxicity against mouse leukemia and human tumor cell lines a
Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations
Campbell, Joanna L. P.,Davies, Christopher D.,Ho?ek, Jan,Ko?ovsky, Pavel,Kysilka, Ond?ej,Popov, Kirill K.,Pour, Milan
, p. 920 - 943 (2022/01/27)
Aldimines, generated in situ from aliphatic, aromatic, and heteroaromatic aldehydes and aliphatic, aromatic, and heteroaromatic primary or secondary amines, can be reduced with trichlorosilane in the presence of dimethylformamide (DMF) as an organocatalys
